个人简介
网投十大信誉排名网站(中国)有限公司教授，博士生导师
教育经历
1996年大连理工大学工学学士；2001年公司理学博士；
工作经历
2002-2003年公司生命科学院微生物遗传博士后；2005-2006年Ohio State University化员工物学博士后，2010年香港理工大学访问教授。在Angew Chem Int Ed, Anal Chem等期刊发表SCI论文60余篇，授权专利5项。入选“教育部新世纪优秀人才”，曾获湖北省自然科学二等奖，公司优秀研究生导师奖，宝钢教育基金奖。
研究方向
1. 荧光分析方法及生物、医学应用，主要兴趣在于上转换荧光（即近红外光长波激发，可见光发射）分析方法和技术。包括两个领域：
1）双光子激发荧光试剂及探针的设计、合成和分析应用。所涉及的材料包括有机小分子和量子点、纳米碳材料、纳米金等无机纳米材料，应用领域包括i）复杂生物基质(体液样本)及食品、环境样本中的定性、定量检测及相互作用研究；ii）活细胞/组织中的生物分子/离子动态成像；iii）用于特定细胞/组织识别的双光子激发荧光材料的设计、合成及功能化。
2）上转换发光无机纳米晶体材料合成及生物传感应用，主要涉及NaYF4基质的稀土掺杂荧光材料。研究内容包括i）上转换纳米荧光材料的设计、合成及表面修饰与功能化；ii）以上转换发光材料为能量供体的共振能量转移（FRET）分析方法、技术平台的研究与构建；iii）建立生物、临床样品（全血样）中的生物大分子均相定量分析及活性研究的新方法、新技术。
2. 纳米光催化材料的合成及其应用。主要包括TiO2基纳米材料的低温化学合成及晶相、形貌控制，材料的物理化学性质及光催化机理研究，污染物降解、光催化自洁等环境应用。
代表成果
1) Zeng Lingyu, Yuan Yunxia, Shen Pei, Wong Kowk-yin,Liu Zhihong*, Graphitic carbon nanoparticles-based single-label nanobeacons, Chemistry-A European Journal, 2013, DOI: 10.1002/chem.201300332. (IF 5.92)
2) Li Zhen, Zeng Lingyu, He Mengyuan,Liu Zhihong*, Graphene-based energy acceptor systems and sensors, Journal of Photochemistry and Photobiology C: Reviews, 2013, Review Article Invited by Editor-in-Chief (IF 10.36)
3) Wang Yuhui, Wu Zhengjun, Liu Zhihong*, Upconversion Fluorescence Resonance Energy Transfer Biosensor with Aromatic Polymer Nanospheres as the Lable-Free Energy Acceptor, Analytical Chemistry 2013, 85, 258-264. (IF 5.86)
4) Wang Yuhui, Shen Pei, Li Chunya, Wang Yanying,Liu Zhihong*, Upconversion FRET-based biosensor for ultrasensitive detection of matrix metalloproteinases-2 (MMP-2) in blood, Analytical Chemistry 2012, 84, 1466-1473 (IF 5.86)
5) Yuan Yunxia, Liu Zhihong*, An effective approach to enhanced energy-transfer efficiency from up-converting phosphors and increased assay sensitivity, Chemical Communications 2012, 48 (60), 7510-7512. (IF 6.17)
6) Dong Xiaohu, Ji Hee Han, Cheol Ho Heo, Hwan Myung Kim, Liu Zhihong*, Bong Rae Cho, Dual-color Imaging of Magnesium/Calcium Ion Activities with Two-Photon Fluorescent Probes. Analytical Chemistry 2012, 84, 8110-8113 (IF 5.86)
7) Chen, Dugang; Zhong, Cheng; Dong, Xiaohu, Liu Zhihong, Qin Jingui, A new building block, bis(thiophene vinyl)-pyrimidine, for constructing excellent two-photon absorption materials: synthesis, crystal structure and properties. Journal of Materials Chemistry, 2012, 22, 4343-4348 (IF 5.97)
8) Wang Yuhui, Bao Lei, Liu Zhihong*, Pang Daiwen, Aptamer biosensor based on fluorescence resonance energy transfer from upconverting phosphors to carbon nanoparticles for thrombin detection in human plasma, Analytical Chemistry 2011, 83, 8130-8137. (IF 5.86)
9) Peng Jianhong, Wang Yuhui, Wang Jialan, Zhou Xin, Liu Zhihong*, A New Biosensor for Glucose Determination in Serum Based on Up-Converting Fluorescence Resonance Energy Transfer, Biosensors & Bioelectronics, 2011, 28, 414-420. (IF 5.6)
10) Zhang Cuiling, Yuan Yunxia, Zhang Shiming, Wang Yuhui, Liu Zhihong*,Biosensing Platform Based on Fluorescence Resonance Energy Transfer from Upconverting Nano-crystals to Graphene Oxide, Angew. Chem. Int. Ed. 2011, 50, 6851-6854. (IF 13.46)
11) Liu Lingzhi, Li Hui, Qiu Ting, Zhou Guohua, Wong Kwok-Yin, He Zhike, Liu Zhihong*, Construction of a molecular beacon based on two-photon excited fluorescence resonance energy transfer with quantum dot as donor, Chemical Communications 2011, 47, 2622 -2624. (IF 6.17)
12) Liu Lingzhi, Dong Xiaohu, Lian Wenlong, Peng Xiaoniu, Liu Zhihong*, He Zhike, Wang Ququan, Homogeneous competitive hybridization assay based on two-photon excitation fluorescence resonance energy transfer, Analytical Chemistry 2010, 82, 1381-1388 (IF 5.86)
13) Dong Xiaohu, Yang Yiyao, Sun Jian, Liu Zhihong*, Liu Bifeng Two-photon excited fluorescent probes for calcium based on internal charge transfer, Chemical Communications 2009, 3883-3885 (IF 6.17)
14) Liu Lingzhi, Shao Mei, Dong Xiaohu, Liu Zhihong*, Wang Ququan, Homogeneous immunoassay based on two-photon excitation fluorescence resonance energy transfer, Analytical Chemistry 2008, 80,7735-7741 (IF 5.86)
15) Wang Jingyu, Liu Zhihong*, Cai Ruxiu, A new role for Fe3+ in TiO2 hydrosol: Accelerated photodegradation of dyes under visible light, Environmental Science & Technology 2008, 42, 5759-5764 (IF 5.23)
